Development of Copper Catalyzed Alkylboron Oxidative Homocoupling

Subject Area

Chemistry

Description

Carbon-carbon bonding is considered one of the most important chemical reactions in organic chemistry. The goal of this project is to perform a new carbon-carbon coupling reaction using copper to catalyze a radical boron reaction to form a sp3–sp3 C-C bond. In the past, boron has been used to form C-C bonds. However, what is new about this research is the geometry of the two carbon atoms being joined. Many experiments have successfully coupled two sp2 carbons, and one experiment was able to couple an sp2 carbon and an sp3 carbon; however, this experiment seeks to couple two sp3 carbons. As far as the researchers are aware, this is the first presentation of sp3-sp3 C-C bonding using the proposed mechanism.

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Development of Copper Catalyzed Alkylboron Oxidative Homocoupling

Carbon-carbon bonding is considered one of the most important chemical reactions in organic chemistry. The goal of this project is to perform a new carbon-carbon coupling reaction using copper to catalyze a radical boron reaction to form a sp3–sp3 C-C bond. In the past, boron has been used to form C-C bonds. However, what is new about this research is the geometry of the two carbon atoms being joined. Many experiments have successfully coupled two sp2 carbons, and one experiment was able to couple an sp2 carbon and an sp3 carbon; however, this experiment seeks to couple two sp3 carbons. As far as the researchers are aware, this is the first presentation of sp3-sp3 C-C bonding using the proposed mechanism.