Alloy Au/Ag Nanoparticles Introduced to S. Cerevisiae Cells In Vitro
Faculty Sponsor(s)
Brian Gilbert
Location
Jereld R. Nicholson Library: Grand Avenue
Subject Area
Chemistry
Description
For the past two summers I have been working with Professor Brian Gilbert and fellow students in an effort to create a nanoparticle therapeutic delivery system. We have accomplished making silver-coated gold nanoparticles of varying sizes ranging from 30nm to 100nm. We want to introduce nanoparticles to yeast cells since the cells resemble human cells and grow rapidly, making them easy to work with. In order to do this, we have worked with breaking down the cell wall in order for the nanoparticles to enter the cell more easily, and we have also attached antibodies to make the nanoparticles more attractive to the cell. To track the activity of the nanoparticles in the cells, TAG molecules are attached to the nanoparticle that can be used with SERS.
Recommended Citation
Alfaro, Ana and Gilbert, Brian D., "Alloy Au/Ag Nanoparticles Introduced to S. Cerevisiae Cells In Vitro" (2019). Linfield University Student Symposium: A Celebration of Scholarship and Creative Achievement. Event. Submission 84.
https://digitalcommons.linfield.edu/symposium/2019/all/84
Alloy Au/Ag Nanoparticles Introduced to S. Cerevisiae Cells In Vitro
Jereld R. Nicholson Library: Grand Avenue
For the past two summers I have been working with Professor Brian Gilbert and fellow students in an effort to create a nanoparticle therapeutic delivery system. We have accomplished making silver-coated gold nanoparticles of varying sizes ranging from 30nm to 100nm. We want to introduce nanoparticles to yeast cells since the cells resemble human cells and grow rapidly, making them easy to work with. In order to do this, we have worked with breaking down the cell wall in order for the nanoparticles to enter the cell more easily, and we have also attached antibodies to make the nanoparticles more attractive to the cell. To track the activity of the nanoparticles in the cells, TAG molecules are attached to the nanoparticle that can be used with SERS.
