Faculty Sponsor(s)
Brian Gilbert
Location
Jereld R. Nicholson Library: Grand Avenue
Subject Area
Chemistry
Description
Gold nanoparticles were prepared with the potential to operate as drug delivery vehicles. Surface-enhanced Raman spectroscopy (SERS) is of particular importance as an optical bioimaging technique due to its ability to allow deep and high-resolution volumetric imaging of biological tissues. Characterization of the gold nanoparticles with para-mercaptobenzoic acid (pMBA), a SERS active molecule, silver, and a phospholipid bilayer was done using Raman and UV-vis spectroscopy and particle size analysis. Our results indicate successful coating of the gold nanoparticles and show consistent pMBA Raman spectroscopy peaks that will allow for the nanoparticle use in-vivo to be monitored.
Recommended Citation
Smith, Allison B. and Gilbert, Brian, "Synthesis and Characterization of Coated Gold Nanoparticles with Embedded SERS Tags" (2017). Linfield University Student Symposium: A Celebration of Scholarship and Creative Achievement. Event. Submission 11.
https://digitalcommons.linfield.edu/symposium/2017/all/11
Synthesis and Characterization of Coated Gold Nanoparticles with Embedded SERS Tags
Jereld R. Nicholson Library: Grand Avenue
Gold nanoparticles were prepared with the potential to operate as drug delivery vehicles. Surface-enhanced Raman spectroscopy (SERS) is of particular importance as an optical bioimaging technique due to its ability to allow deep and high-resolution volumetric imaging of biological tissues. Characterization of the gold nanoparticles with para-mercaptobenzoic acid (pMBA), a SERS active molecule, silver, and a phospholipid bilayer was done using Raman and UV-vis spectroscopy and particle size analysis. Our results indicate successful coating of the gold nanoparticles and show consistent pMBA Raman spectroscopy peaks that will allow for the nanoparticle use in-vivo to be monitored.
