Faculty Sponsor
Brian Gilbert
Location
Jereld R. Nicholson Library
Date
5-11-2012 3:00 PM
End Date
5-11-2012 4:30 PM
Subject Area
Chemistry (general)
Description
Distinguished from standard techniques of bioanalysis, the high specificity of Raman spectroscopy provides information on a molecular level without tagging the biomolecule. Surface-enhanced Raman spectroscopy (SERS) is a surface-sensitive technique that enhances Raman scattering by a factor up to 1011, increasing sensitivity when molecules are adsorbed to silver (Ag) and gold (Au) nanoparticles. To characterize the physical and chemical properties of di- and tri-peptides, SERS spectra of Gly-Tyr, Phe-Gly-Gly and Val-Tyr-Val were obtained by adsorbing the peptides to Ag and Au nanoparticles in aqueous solutions. The predominance of vibrations and dominant peaks originating in individual amino acid residues and side chains indicated that all the peptides adsorbed to the Ag and Au surfaces at the amino terminus.
Recommended Citation
Stovall, Stephanie L., "Surface-Enhanced Raman Spectroscopy of Peptides Adsorbed on Silver and Gold Nanoparticles in Aqueous Solutions" (2012). Science and Social Sciences. Event. Submission 27.
https://digitalcommons.linfield.edu/studsymp_sci/2012/all/27
Surface-Enhanced Raman Spectroscopy of Peptides Adsorbed on Silver and Gold Nanoparticles in Aqueous Solutions
Jereld R. Nicholson Library
Distinguished from standard techniques of bioanalysis, the high specificity of Raman spectroscopy provides information on a molecular level without tagging the biomolecule. Surface-enhanced Raman spectroscopy (SERS) is a surface-sensitive technique that enhances Raman scattering by a factor up to 1011, increasing sensitivity when molecules are adsorbed to silver (Ag) and gold (Au) nanoparticles. To characterize the physical and chemical properties of di- and tri-peptides, SERS spectra of Gly-Tyr, Phe-Gly-Gly and Val-Tyr-Val were obtained by adsorbing the peptides to Ag and Au nanoparticles in aqueous solutions. The predominance of vibrations and dominant peaks originating in individual amino acid residues and side chains indicated that all the peptides adsorbed to the Ag and Au surfaces at the amino terminus.