Publication Date

2006

Disciplines

Cell Biology

Abstract

The large GTPase dynamin, long known for its role in endocytosis, has most recently been implicated as a facilitator of cell migration and invasion. Recent observations link dynamin to the cycle of membrane expansion and retraction essential for cell motility. Its role in actin polymerization, membrane deformation and vesiculation, and focal adhesion dynamics are all important for this process, and the new findings provide exciting directions for studies of this ubiquitous and diverse protein family.

Document Type

Published Version

Comments

This article is the publisher-created version, also considered to be the final version or the version of record. It includes value-added elements provided by the publisher, such as copy editing, layout changes, and branding consistent with the rest of the publication.

Original Citation

Anne E. Kruchten & Mark A. McNiven
Dynamin as a mover and pincher during cell migration and invasion.
Journal of Cell Science, 2006, volume 119, issue 9, pages 1683-1690
doi:10.1242/​jcs.02963

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Cell Biology Commons

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