Submission Title

Genome Annotation of Drosophila takahashi

Location

Jereld R. Nicholson Library: Grand Avenue

Subject Area

Biology

Description

The Genomics Education Partnership (GEP) seeks to train faculty and undergraduates in the use of modern genomics techniques, with a particular emphasis on genome annotation. There are many species with sequenced but unannotated genomes, meaning that the order of As, Gs, Ts, and Cs is known, but the location of gene features is ambiguous. Annotated genomes enable researchers to address specific questions exploring evolutionary histories and principles of genome organization and gene expression. Genomes can be annotated with the use of a well-annotated model organism reference sequence, such as the annotated sequence of Drosophila melanogaster. My research focuses on two segments of the Drosophila takahashi genome. Practice annotations were carried out to learn how to apply bioinformatics tools to the annotation of novel sequences. A number of tools are available for genome annotation, including the UCSC Genome Browser, Flybase, BLAST, and a custom tool, the Gene Record Finder. All of these tools have been used to discover gene features in the D. takahashi genome. Future work will document gene and genome evolution among these Drosophila species and interrogate key principles of gene expression.

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May 17th, 9:30 AM May 17th, 11:00 AM

Genome Annotation of Drosophila takahashi

Jereld R. Nicholson Library: Grand Avenue

The Genomics Education Partnership (GEP) seeks to train faculty and undergraduates in the use of modern genomics techniques, with a particular emphasis on genome annotation. There are many species with sequenced but unannotated genomes, meaning that the order of As, Gs, Ts, and Cs is known, but the location of gene features is ambiguous. Annotated genomes enable researchers to address specific questions exploring evolutionary histories and principles of genome organization and gene expression. Genomes can be annotated with the use of a well-annotated model organism reference sequence, such as the annotated sequence of Drosophila melanogaster. My research focuses on two segments of the Drosophila takahashi genome. Practice annotations were carried out to learn how to apply bioinformatics tools to the annotation of novel sequences. A number of tools are available for genome annotation, including the UCSC Genome Browser, Flybase, BLAST, and a custom tool, the Gene Record Finder. All of these tools have been used to discover gene features in the D. takahashi genome. Future work will document gene and genome evolution among these Drosophila species and interrogate key principles of gene expression.