Submission Title

Zebrafish Rheotaxis in the Presence of GABA Receptor Modulators

Location

Jereld R. Nicholson Library: Grand Avenue

Subject Area

Biology

Description

Our preliminary data suggest that both A and B type receptors for gamma-aminobutyric acid (GABA), a neurotransmitter found in inhibitory pathways, are present within the lateral line system of zebrafish (Danio rerio). However, the function of these receptors is unknown. Zebrafish use their lateral line to perform rheotaxis, orientation into an oncoming current. This sensory system is comprised of neuromasts with protruding cilia from hair cells. As moving water deflects the cilia, hair cells become activated, and then they can transduce a signal to cells of the central nervous system.

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Zebrafish Rheotaxis in the Presence of GABA Receptor Modulators

Jereld R. Nicholson Library: Grand Avenue

Our preliminary data suggest that both A and B type receptors for gamma-aminobutyric acid (GABA), a neurotransmitter found in inhibitory pathways, are present within the lateral line system of zebrafish (Danio rerio). However, the function of these receptors is unknown. Zebrafish use their lateral line to perform rheotaxis, orientation into an oncoming current. This sensory system is comprised of neuromasts with protruding cilia from hair cells. As moving water deflects the cilia, hair cells become activated, and then they can transduce a signal to cells of the central nervous system.