Location

Jereld R. Nicholson Library: Grand Avenue

Subject Area

Chemistry

Description

TOR1 is known to extend chronological lifespan in S. cerevisiae. Δtor1 deletion was studied via chronological lifespan assay and environmental oxidative stress test. This deletion was confirmed via growth in selective media and through deletion check primers. The Δtor1 deletion created demonstrated similar growth and cellular response to environmental oxidative stress as previously put forth by Bonawitz et al. and Pan et al.

In this work, partial inhibition of TOR by deletion of TOR1 is studied through S. cerevisiae longevity via a chronological lifespan assay, with intention of studying the double gene deletion strains of Δlys7tor1, Δsod1tor1, Δsod2tor1, and Δctr1tor1. Double gene deletion strains of Δlys7tor1, Δsod1tor1, Δsod2tor1, and Δctr1tor1 are not well-characterized for their effects on S. cerevisiae longevity.

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May 5th, 3:00 PM May 5th, 4:30 PM

Effects of Δtor1 on Yeast Longevity via Chronological Lifespan Assay

Jereld R. Nicholson Library: Grand Avenue

TOR1 is known to extend chronological lifespan in S. cerevisiae. Δtor1 deletion was studied via chronological lifespan assay and environmental oxidative stress test. This deletion was confirmed via growth in selective media and through deletion check primers. The Δtor1 deletion created demonstrated similar growth and cellular response to environmental oxidative stress as previously put forth by Bonawitz et al. and Pan et al.

In this work, partial inhibition of TOR by deletion of TOR1 is studied through S. cerevisiae longevity via a chronological lifespan assay, with intention of studying the double gene deletion strains of Δlys7tor1, Δsod1tor1, Δsod2tor1, and Δctr1tor1. Double gene deletion strains of Δlys7tor1, Δsod1tor1, Δsod2tor1, and Δctr1tor1 are not well-characterized for their effects on S. cerevisiae longevity.

 

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